Database

Disease	A B C D E F G H I J K L M N O P Q R S T U V W X Y Z [0-9]
Gene	A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

IL6R

Gene name: interleukin 6 receptor
OMIM ID: 147880
Chromosome location: 1q21.3

Disease/Phenotype

Reference transcript

DNA Change

c.1073A>C

A.A. Change

p.Asp358Ala

Exon/Intron

exon 9

Variation Type

substitution

Reference SNP

Cases

199 IBD patients

Controls

311 healthy controls

Frequency

Allele/Genotype	Frequency in cases	Frequency in controls	OR (95%CI)	P-value
CC	20 (10.15%)	33 (10.89%)
CA	85 (43.15%)	125 (41.25%)	1.04 (0.73-1.5) (Dominant)	0.80
AA	92 (46.70%)	145 (47.85%)	0.92 (0.51-1.66) (Recessive)	0.79

Reference

Senhaji N, Serrano A, Badre W, Serbati N, Karkouri M, Zaid Y, Nadifi S, Martin J. Association of inflammatory cytokine gene polymorphisms with inflammatory bowel disease in a Moroccan cohort.
Genes Immun. 2016 Jan-Feb;17(1):60-5. doi: 10.1038/gene.2015.52. Epub 2015 Dec 3.