SLC30A8

Gene name: solute carrier family 30 (zinc transporter), member 8
OMIM ID: 611145
Chromosome location: 8q24.11

Polymorphisms

Disease/Phenotype	Diabetes mellitus, insulin-resistant, with acanthosis nigricans
Reference transcript	NM_001172811.1
DNA Change	c.826C>A
A.A. Change
Exon/Intron	exon 10
Variation Type	substitution
Reference SNP	rs13266634
Cases	1193 T2D cases
Controls	1055 normoglycaemic controls
Frequency	Allele/Genotype Frequency in cases Frequency in controls OR (95%CI) P-value C 82.8% 83.2% Recessive: 0.94 (0.78-1.15) 0.56
Comments	polymorphism not associated with type 2 diabetes in the Moroccan sample population
Reference	Cauchi S, Ezzidi I, El Achhab Y, Mtiraoui N, Chaieb L, Salah D, Nejjari C, Labrune Y, Yengo L, Beury D, Vaxillaire M, Mahjoub T, Chikri M, Froguel P.European genetic variants associated with type 2 diabetes in North African Arabs. Diabetes Metab. 2012 Mar 29.

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