Disease A B C D E F G H I J K L M N O P Q R S T U V W X Y Z [0-9]
Gene A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Inflammatory bowel disease 17, protection against

OMIM:612261
Mode of inheritance:Multifactorial
Disease classification:Diseases of the digestive system


Polymorphisms

Gene symbolIL23R
Reference transcriptNM_144701.2
DNA Changec.929T>C
A.A. Changep.Leu310Pro
Exon/Intronexon 7
Variation Typesubstitution
Reference SNPrs7530511
Cases69 with Crohn’s disease
Controls115 unrelated healthy controls
Frequency
Allele/GenotypeFrequency in casesFrequency in controlsOR (95%CI)P-value
C82.6%91.3%1
T17.4%8.7%0.74 (0.31-1.73)0.48
CC76.8%85.2%1
CT23.2%12.2%1.06 (0.41-2.68)0.91
TT0.0%2.6%0.26 (0.01-5.19)0.38
ReferenceSerbati N, Senhaji N, Diakite B, Badre W, Nadifi S.IL23R and ATG16L1 variants in Moroccan patients with inflammatory bowel disease.
BMC Res Notes. 2014 Aug 26;7:570.