ATG16L1

Gene name: autophagy related 16-like 1 (S. cerevisiae)
OMIM ID: 610767
Chromosome location: 2q37.1

Polymorphisms

Disease/Phenotype	Inflammatory bowel disease 10
Reference transcript	NM_030803.6
DNA Change	c.898A>G
A.A. Change	p.Thr300Ala
Exon/Intron	exon 9
Variation Type	substitution
Reference SNP	rs2241880
Cases	69 with Crohn’s disease
Controls	115 unrelated healthy controls
Frequency	Allele/Genotype Frequency in cases Frequency in controls OR (95%CI) P-value A 54.3% 59.1% 1 G 45.7% 40.9% 1.22 (0.79-1.86) 0.36 AA 23.2% 26.1% 1 AG 62.3% 66.1% 1.06 (0.52-2.16) 0.87 GG 14.5% 7.8% 2.08 (0.70-6.17) 0.19
Reference	Serbati N, Senhaji N, Diakite B, Badre W, Nadifi S.IL23R and ATG16L1 variants in Moroccan patients with inflammatory bowel disease. BMC Res Notes. 2014 Aug 26;7:570.

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