GSTT1

Gene name: glutathione S-transferase theta 1
OMIM ID: 600436
Chromosome location: 22q11.23

Polymorphisms

Disease/Phenotype	Leukemia, chronic myeloid
DNA Change	null or non-null genotype
A.A. Change
Variation Type	others
Cases	92
Controls	93
Frequency	Allele/Genotype Frequency in cases Frequency in controls OR (95%CI) P-value non-null genotype 82.6% 90.3% 1 null genotype 17.4% 9.7% 1.97 (0.82-4.71) 0.13
Reference	Kassogue Y, Dehbi H, Quachouh M, Quessar A, Benchekroun S, Nadifi S.Association of glutathione S-transferase (GSTM1 and GSTT1) genes with chronic myeloid leukemia. Springerplus. 2015 May 1;4:210.

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Disease/Phenotype	Inflammatory bowel disease, susceptibility to
DNA Change	null or non-null genotype
A.A. Change
Variation Type	others
Cases	110 patients diagnosed with IBD
Controls	100 blood donors were used as controls
Frequency	Allele/Genotype Frequency in cases Frequency in controls OR (95%CI) P-value Present 70 83 1 Null 40 17 2.79 (1.45-5.34)
Reference	Senhaji N, Kassogue Y, Fahimi M, Serbati N, Badre W, Nadifi S. Genetic Polymorphisms of Multidrug Resistance Gene-1 (MDR1/ABCB1) and Glutathione S-Transferase Gene and the Risk of Inflammatory Bowel Disease among Moroccan Patients. Mediators Inflamm. 2015;2015:248060. doi: 10.1155/2015/248060. Epub 2015 Oct 28.

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  Variant not named according to HGVS recommendations