Disease A B C D E F G H I J K L M N O P Q R S T U V W X Y Z [0-9]
Gene A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

GSTM1

Gene name: glutathione S-transferase mu 1
OMIM ID: 138350
Chromosome location: 1p13.3

Polymorphisms

Disease/PhenotypeLeukemia, chronic myeloid
DNA Changenull or non-null genotype
A.A. Change
Variation Typeothers
Cases92
Controls93
Frequency
Allele/GenotypeFrequency in casesFrequency in controlsOR (95%CI)P-value
non-null genotype51.1%59.1%1
null genotype48.9%40.9%1.4 (0.78-2.48)0.271
ReferenceKassogue Y, Dehbi H, Quachouh M, Quessar A, Benchekroun S, Nadifi S.Association of glutathione S-transferase (GSTM1 and GSTT1) genes with chronic myeloid leukemia.
Springerplus. 2015 May 1;4:210.

Disease/PhenotypeInflammatory bowel disease, susceptibility to
DNA Changenull or non-null genotype
A.A. Change
Variation Typeothers
Cases110 patients diagnosed with IBD
Controls100 blood donors were used as controls
Frequency
Allele/GenotypeFrequency in casesFrequency in controlsOR (95%CI)P-value
Present48491
Null62511.24 (0.72-2.13)
ReferenceSenhaji N, Kassogue Y, Fahimi M, Serbati N, Badre W, Nadifi S. Genetic Polymorphisms of Multidrug Resistance Gene-1 (MDR1/ABCB1) and Glutathione S-Transferase Gene and the Risk of Inflammatory Bowel Disease among Moroccan Patients.
Mediators Inflamm. 2015;2015:248060. doi: 10.1155/2015/248060. Epub 2015 Oct 28.


  Variant not named according to HGVS recommendations