EGFR

Gene name: epidermal growth factor receptor
OMIM ID: 131550
Chromosome location: 7p11.2

Polymorphisms

Disease/Phenotype	Nasopharyngeal carcinoma, susceptibility to
Reference transcript	NM_005228.3
DNA Change	c.2361G>A
A.A. Change
Exon/Intron	exon 20
Variation Type	substitution
Reference SNP	rs1050171
Cases	60 NPC cases
Controls
Frequency	Allele/Genotype Frequency in cases Frequency in controls OR (95%CI) P-value GG 5 (8.4%) GA 16 (26.6%) AA 39 (65%)
Reference	Naji F, Attaleb M, Laantri N, Benchakroun N, El Gueddari B, Benider A, Azeddoug H, Ennaji MM, El Mzibri M, Khyatti M.Identification of G2607A mutation in EGFR gene with a significative rate in Moroccan patients with nasopharyngeal carcinoma. Cell Mol Biol (Noisy-le-grand). 2010 Dec 15;56 Suppl:OL1442-6.

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