Mendelian Diseases
Multifactorial Diseases
Disease A B C D E F G H I J K L M N O P Q R S T U V W X Y Z [0-9]
Gene A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

CFB

Gene name: complement factor B
OMIM ID: 138470
Chromosome location: 6p21.33

Polymorphisms

Disease/PhenotypeDiabetes mellitus, type 2 (T2DM), susceptibility to
Reference transcriptNM_001710.5
DNA Changec.450A>G
A.A. Change
Variation Typesubstitution
Reference SNPrs1048709
Cases1193 T2D cases
Controls1055 normoglycaemic controls
Frequency
Allele/GenotypeFrequency in casesFrequency in controlsOR (95%CI)P-value
G90.6%91.1%Log-additive: 0.95 (0.76-1.19)0.66
Commentspolymorphism not associated with type 2 diabetes in the Moroccan sample population
ReferenceCauchi S, Ezzidi I, El Achhab Y, Mtiraoui N, Chaieb L, Salah D, Nejjari C, Labrune Y, Yengo L, Beury D, Vaxillaire M, Mahjoub T, Chikri M, Froguel P.European genetic variants associated with type 2 diabetes in North African Arabs.
Diabetes Metab. 2012 Mar 29.