HHEX

Gene name: hematopoietically expressed homeobox
OMIM ID: 604420
Chromosome location: 10q23.33

Polymorphisms

Disease/Phenotype	Diabetes mellitus, type 2 (T2DM), susceptibility to
Reference transcript	NC_000010.10
DNA Change	g.94462882C>T
A.A. Change
Variation Type	substitution
Reference SNP	rs1111875
Cases	1193 T2D cases
Controls	1055 normoglycaemic controls
Frequency	Allele/Genotype Frequency in cases Frequency in controls OR (95%CI) P-value C 67.3% 67.0% Dominant: 1.1 (0.83-1.45) 0.49
Comments	polymorphism not associated with type 2 diabetes in the Moroccan sample population
Reference	Cauchi S, Ezzidi I, El Achhab Y, Mtiraoui N, Chaieb L, Salah D, Nejjari C, Labrune Y, Yengo L, Beury D, Vaxillaire M, Mahjoub T, Chikri M, Froguel P.European genetic variants associated with type 2 diabetes in North African Arabs. Diabetes Metab. 2012 Mar 29.

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