NOTCH2
Gene name: notch 2OMIM ID: 600275
Chromosome location: 1p12-p11
Polymorphisms
| Disease/Phenotype | Diabetes mellitus, type 2 (T2DM), susceptibility to | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Reference transcript | NC_000001.10 | ||||||||||
| DNA Change | g.120517959G>T | ||||||||||
| A.A. Change | |||||||||||
| Variation Type | substitution | ||||||||||
| Reference SNP | rs10923931 | ||||||||||
| Cases | 1193 T2D cases | ||||||||||
| Controls | 1055 normoglycaemic controls | ||||||||||
| Frequency |
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| Comments | polymorphism not associated with type 2 diabetes in the Moroccan sample population | ||||||||||
| Reference | Cauchi S, Ezzidi I, El Achhab Y, Mtiraoui N, Chaieb L, Salah D, Nejjari C, Labrune Y, Yengo L, Beury D, Vaxillaire M, Mahjoub T, Chikri M, Froguel P.European genetic variants associated with type 2 diabetes in North African Arabs. Diabetes Metab. 2012 Mar 29. |