ADAMTS9

Gene name: ADAM metallopeptidase with thrombospondin type 1 motif, 9
OMIM ID: 605421
Chromosome location: 3p14.1

Polymorphisms

Disease/Phenotype	Diabetes mellitus, type 2 (T2DM), susceptibility to
Reference transcript	NC_000003.11
DNA Change	g.64705365C>T
A.A. Change
Variation Type	substitution
Reference SNP	rs6795735
Cases	1193 T2D cases
Controls	1055 normoglycaemic controls
Frequency	Allele/Genotype Frequency in cases Frequency in controls OR (95%CI) P-value C 32.3 % 31.8% 1.06 (0.92-1.22) 0.45 (Log-additive)
Comments	Polymorphism associated with type 2 diabetes in the Moroccan sample population
Reference	Cauchi S, Ezzidi I, El Achhab Y, Mtiraoui N, Chaieb L, Salah D, Nejjari C, Labrune Y, Yengo L, Beury D, Vaxillaire M, Mahjoub T, Chikri M, Froguel P.European genetic variants associated with type 2 diabetes in North African Arabs. Diabetes Metab. 2012 Mar 29.

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Disease/Phenotype	Diabetes mellitus, type 2 (T2DM), susceptibility to
Reference transcript	NC_000003.11
DNA Change	g.64711904C>T
A.A. Change
Variation Type	substitution
Reference SNP	rs4607103
Cases	1193 T2D cases
Controls	1055 normoglycaemic controls
Frequency	Allele/Genotype Frequency in cases Frequency in controls OR (95%CI) P-value C 64.7% 62.6% 1.22 (1.01-1.47) 0.04 (Recessive)
Comments	Polymorphism associated with type 2 diabetes in the Moroccan sample population
Reference	Cauchi S, Ezzidi I, El Achhab Y, Mtiraoui N, Chaieb L, Salah D, Nejjari C, Labrune Y, Yengo L, Beury D, Vaxillaire M, Mahjoub T, Chikri M, Froguel P.European genetic variants associated with type 2 diabetes in North African Arabs. Diabetes Metab. 2012 Mar 29.

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