Mendelian Diseases
Multifactorial Diseases
Disease A B C D E F G H I J K L M N O P Q R S T U V W X Y Z [0-9]
Gene A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Inflammatory bowel disease 13

OMIM:612244
Mode of inheritance:Multifactorial
Disease classification:Diseases of the digestive system


Polymorphisms

Gene symbolABCB1
Reference transcriptNM_000927.4
DNA Changec.1236T>C
A.A. Changep.Gly412Gly
Exon/Intronexon 13
Variation Typesubstitution
Reference SNPrs1128503
Cases110 patients diagnosed with IBD
Controls100 blood donors were used as controls
Frequency
Allele/GenotypeFrequency in casesFrequency in controlsOR (95%CI)P-value
C1451351
T75651.07 (0.71-1.61)
ReferenceSenhaji N, Kassogue Y, Fahimi M, Serbati N, Badre W, Nadifi S. Genetic Polymorphisms of Multidrug Resistance Gene-1 (MDR1/ABCB1) and Glutathione S-Transferase Gene and the Risk of Inflammatory Bowel Disease among Moroccan Patients.
Mediators Inflamm. 2015;2015:248060. doi: 10.1155/2015/248060. Epub 2015 Oct 28.
Gene symbolABCB1
Reference transcriptNM_000927.4
DNA Changec.3435T>C
A.A. Changep.(=)
Exon/Intronexon 27
Variation Typesubstitution
Reference SNPrs1045642
Cases110 patients diagnosed with IBD
Controls100 blood donors were used as controls
Frequency
Allele/GenotypeFrequency in casesFrequency in controlsOR (95%CI)P-value
C145671
T75530.65 (0.41-1.03)
ReferenceSenhaji N, Kassogue Y, Fahimi M, Serbati N, Badre W, Nadifi S. Genetic Polymorphisms of Multidrug Resistance Gene-1 (MDR1/ABCB1) and Glutathione S-Transferase Gene and the Risk of Inflammatory Bowel Disease among Moroccan Patients.
Mediators Inflamm. 2015;2015:248060. doi: 10.1155/2015/248060. Epub 2015 Oct 28.