Nasopharyngeal carcinoma, susceptibility to
OMIM:161550Mode of inheritance:Multifactorial
Disease classification:Neoplasms
Polymorphisms
| Gene symbol | EGFR | ||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Reference transcript | NM_005228.3 | ||||||||||||||||||||
| DNA Change | c.2361G>A | ||||||||||||||||||||
| A.A. Change | |||||||||||||||||||||
| Exon/Intron | exon 20 | ||||||||||||||||||||
| Variation Type | substitution | ||||||||||||||||||||
| Reference SNP | rs1050171 | ||||||||||||||||||||
| Cases | 60 NPC cases | ||||||||||||||||||||
| Controls | |||||||||||||||||||||
| Frequency |
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| Reference | Naji F, Attaleb M, Laantri N, Benchakroun N, El Gueddari B, Benider A, Azeddoug H, Ennaji MM, El Mzibri M, Khyatti M.Identification of G2607A mutation in EGFR gene with a significative rate in Moroccan patients with nasopharyngeal carcinoma. Cell Mol Biol (Noisy-le-grand). 2010 Dec 15;56 Suppl:OL1442-6. |