Glioblastoma
OMIM:137800Mode of inheritance:Sporadic
Disease classification:Neoplasms
Mutations
| Gene Symbol | TP53 |
|---|---|
| Reference transcript | NM_000546.5 |
| DNA Change | c.818G>A |
| A.A. Change | p.R273H |
| Exon/Intron | exon 8 |
| Mutation Type | substitution |
| Reference | Hilmani S, Abidi O, Benrahma H, Karkouri M, Sahraoui S, El Azhari A, Barakat A.Clinicopathological Features and Molecular Analysis of Primary Glioblastomas in Moroccan Patients. J Mol Neurosci. 2012 Aug 4. |
| Gene Symbol | TP53 |
|---|---|
| Reference transcript | NM_000546.5 |
| DNA Change | c.916 C>T |
| A.A. Change | p.R306X |
| Exon/Intron | exon 8 |
| Mutation Type | substitution |
| Reference | Hilmani S, Abidi O, Benrahma H, Karkouri M, Sahraoui S, El Azhari A, Barakat A.Clinicopathological Features and Molecular Analysis of Primary Glioblastomas in Moroccan Patients. J Mol Neurosci. 2012 Aug 4. |
| Gene Symbol | TP53 |
|---|---|
| Reference transcript | NM_000546.5 |
| DNA Change | c.406C>T |
| A.A. Change | p.Q136X |
| Exon/Intron | exon 5 |
| Mutation Type | substitution |
| Reference | Hilmani S, Abidi O, Benrahma H, Karkouri M, Sahraoui S, El Azhari A, Barakat A.Clinicopathological Features and Molecular Analysis of Primary Glioblastomas in Moroccan Patients. J Mol Neurosci. 2012 Aug 4. |